Robert W Robey Selected Research

Therapeutics

4/2024	Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model.
3/2024	Carrier-Free, Amorphous Verteporfin Nanodrug for Enhanced Photodynamic Cancer Therapy and Brain Drug Delivery.
12/2023	The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors.
1/2023	New mechanisms of multidrug resistance: an introduction to the Cancer Drug Resistance special collection.
1/2021	Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms.
1/2021	Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.
1/2021	R-Loop-Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin.
4/2017	Pancreatic Cancer: "A Riddle Wrapped in a Mystery inside an Enigma".
10/2013	Overlapping substrate and inhibitor specificity of human and murine ABCG2.
9/2013	Loss of the proteins Bak and Bax prevents apoptosis mediated by histone deacetylase inhibitors.

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Robert W Robey Research Topics

Disease

51	Neoplasms (Cancer) 04/2024 - 03/2002
15	Breast Neoplasms (Breast Cancer) 12/2023 - 06/2002
6	T-Cell Lymphoma (Lymphoma, T Cell) 10/2016 - 06/2004
4	Glioma (Gliomas) 04/2024 - 02/2013
4	Kidney Neoplasms (Kidney Cancer) 02/2023 - 03/2006
3	Glioblastoma (Glioblastoma Multiforme) 01/2023 - 07/2005
3	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 05/2013 - 07/2010
2	Brain Neoplasms (Brain Tumor) 10/2023 - 01/2023
2	Rhabdomyosarcoma 01/2023 - 01/2021
2	Neuroblastoma 01/2021 - 04/2008
2	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 01/2018
2	Infections 01/2020 - 07/2010
2	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 12/2011 - 01/2010
2	Carcinoma (Carcinomatosis) 08/2009 - 02/2005
2	Renal Cell Carcinoma (Grawitz Tumor) 02/2009 - 07/2004
1	Lymphoma (Lymphomas) 04/2024
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2023
1	Uveal melanoma 01/2021
1	Ovarian Epithelial Carcinoma 01/2021
1	Carcinogenesis 05/2020
1	Mycoplasma Infections 01/2020

Drug/Important Bio-Agent (IBA)

19	ATP-Binding Cassette Transporters (ABC Transporters)IBA 10/2023 - 03/2006
18	Proteins (Proteins, Gene)FDA Link 07/2023 - 06/2002
17	Adenosine Triphosphate (ATP)IBA 12/2023 - 06/2002
14	Histone Deacetylase InhibitorsIBA 12/2023 - 03/2002
12	romidepsin (FK228)FDA Link 12/2023 - 03/2002
12	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2019 - 07/2004
5	Mitoxantrone (Novantrone)FDA LinkGeneric 08/2009 - 07/2005
4	Photosensitizing Agents (Photosensitizers)IBA 03/2024 - 02/2005
4	multidrug resistance-associated protein 1IBA 10/2019 - 03/2008
4	DepsipeptidesIBA 05/2015 - 03/2002
4	Tyrosine Kinase InhibitorsIBA 08/2010 - 03/2007
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 03/2024 - 02/2005
3	TubulinIBA 01/2018 - 12/2007
3	Vorinostat FDA Link 12/2014 - 12/2011
3	Biomarkers (Surrogate Marker)IBA 06/2014 - 07/2010
3	ErbB Receptors (EGF Receptor)IBA 02/2009 - 03/2007
3	Gefitinib (Iressa)FDA Link 02/2009 - 03/2007
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2024 - 02/2005
2	imidazole ketone erastinIBA 02/2023 - 01/2023
2	PiperazineIBA 02/2023 - 01/2023
2	erastinIBA 02/2023 - 01/2023
2	Phosphotransferases (Kinase)IBA 01/2023 - 01/2021
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2023 - 02/2008
2	olaparibIBA 01/2023 - 01/2012
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 01/2021
2	trametinibIBA 01/2023 - 01/2021
2	PorphyrinsIBA 01/2022 - 10/2019
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2021 - 10/2016
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2021 - 05/2015
2	Messenger RNA (mRNA)IBA 05/2020 - 02/2013
2	Topotecan (Hycamtin)FDA LinkGeneric 06/2014 - 08/2009
2	tariquidar (XR9576)IBA 01/2012 - 02/2011
2	Irinotecan (Camptosar)FDA LinkGeneric 08/2009 - 01/2008
2	alvocidib (flavopiridol)IBA 02/2009 - 01/2008
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 02/2009 - 11/2007
2	Amino Acids FDA Link 02/2009 - 11/2002
2	Methotrexate (Mexate)FDA LinkGeneric 01/2008 - 09/2002
2	Antineoplastic Agents (Antineoplastics)IBA 09/2006 - 06/2004
1	ibrutinibIBA 04/2024
1	Agammaglobulinaemia Tyrosine KinaseIBA 04/2024
1	liposomal doxorubicin (Doxil)FDA Link 04/2024
1	Verteporfin (Visudyne)FDA Link 03/2024
1	AcidsIBA 03/2024
1	Verapamil (Calan)FDA LinkGeneric 12/2023
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 07/2023
1	Investigational DrugsIBA 07/2023
1	RNA (Ribonucleic Acid)IBA 07/2023
1	SolutionsIBA 01/2023
1	TensinsIBA 01/2023
1	CamptothecinIBA 01/2023
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2023
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2023
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2023
1	NSC 724998IBA 01/2023
1	ganitumabIBA 01/2023
1	niraparibIBA 01/2023
1	Drug CombinationsIBA 01/2023
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 05/2022
1	ulixertinibIBA 01/2021
1	lens intrinsic protein MP 38 (MP38)IBA 01/2021
1	taxaneIBA 01/2021
1	ON 01910IBA 01/2021
1	2- (1H- indazol- 4- yl)- 6- (4- methanesulfonylpiperazin- 1- ylmethyl)- 4- morpholin- 4- ylthieno(3,2- d)pyrimidineIBA 01/2021
1	PlatinumIBA 01/2021
1	Vinca AlkaloidsIBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	LeptinIBA 05/2020
1	Estrogen ReceptorsIBA 05/2020
1	Leptin ReceptorsIBA 05/2020
1	Tiopronin (Thiola)FDA Link 01/2020
1	CeramidesIBA 01/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020

Therapy/Procedure

16	Therapeutics 04/2024 - 06/2004
7	Drug Therapy (Chemotherapy) 03/2024 - 09/2006
3	Photochemotherapy (Photodynamic Therapy) 03/2024 - 02/2005
3	Aftercare (After-Treatment) 02/2013 - 12/2007
1	Precision Medicine 07/2023
1	Treatment Delay 01/2021